RAPID KINETICS - STOPPED FLOW AND QUENCHED FLOW

Bio-logic offers many innovations for today's stopped flow and quenched flow experiments. The success of these experiments is made possible by the instruments unique features

• Anaerobic confinement of reactants
• Full computer control of experiments
• Micro litre volume of reactants
• Sub-millisecond dead time

These versatile instruments provide single, double or triple reactant mixing, with variable delay lines. Stopped flow, quenched flow, reactant volumes and sequence timings are all under computer control. Changes to experimental procedures can be made very quickly by a few keystrokes.

SFM stopped flow - full Computer Control

Bio-Logic stopped flow instruments use computer controlled stepping motors to drive syringes. This innovative control gives high precision rate and volume control, completely variable mixing ratios and no overpressure artifacts.

Rapid kinetic reactions can be detected by UV, CD, fluorescence, FTIR and mass spectroscopy. Also by dual detection such as CD plus fluorescence. Typical Bio-Logic experiments include:

• Protein folding
• Conformational changes
• Substrate binding
• Enzyme kinetics
• Second messenger studies

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